The precise role of the PRLR mutation in sweating rate remains to be resolved; however, observations in hairy syndrome cattle would suggest direct secretory control. In studies where the slick haplotype has been introgressed into Holstein dairy cattle, slick haired animals demonstrate higher milk yields than nonslick contemporaries14,20. These effects are assumed to be due to enhanced thermotolerance, with one study presenting winter milk yield data for which there was no apparent difference between slick and nonslick cows20.The molecular mechanisms by which the PRL and PRLR mutations could exert their effects remain unclear.
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